How Does the 2027 INFINITI QX65 Compare to the Lexus RX 350?

Shoppers comparing the 2027 INFINITI QX65 vs. the 2026 Lexus RX 350 will find two capable mid-size luxury crossovers with distinct personalities. The all-new QX65 stands out with its fastback design, standard all-wheel drive across all trims, a 12.3-inch touchscreen, and a more generous standard feature set. The Lexus RX 350 offers a refined, traditional luxury SUV experience with a slightly lower entry price, though AWD costs extra and premium features require higher trim levels. For Denver and Highlands Ranch drivers who want bold styling, all-weather confidence, and exceptional value, the 2027 INFINITI QX65 makes a compelling case.

2027 INFINITI QX65 Compared to the 2026 Lexus RX 350

If you’re shopping for a mid-size luxury SUV in the Denver area and you’ve been drawn to bold, coupe-inspired styling, two names are likely at the top of your list: the all-new 2027 INFINITI QX65 (starting MSRP $53,990) and the 2026 Lexus RX 350 (starting MSRP $52,375). Both are strong contenders in the two-row luxury crossover segment, but they take very different approaches to design, technology, and the overall ownership experience. The team at Mike Ward INFINITI in Highlands Ranch breaks down how these two vehicles stack up so you can make the most informed decision possible.

Exterior Design

The 2027 INFINITI QX65 is one of the most visually striking entries in the luxury SUV market. Built around INFINITI’s Artistry in Motion design language, it features a dramatic arching fastback roofline, a bold three-dimensional grille with an illuminated INFINITI emblem, and an exclusive Sunfire Red paint finish inspired by the legendary Nissan GT-R. The QX65 draws a direct design lineage from INFINITI’s iconic FX lineup, giving it a genuinely athletic presence on the road.

The Lexus RX 350 takes a more conventional approach, featuring the brand’s updated “spindle body” design with sharp LED headlights and a refined, upscale appearance. It reads as a traditional luxury SUV — handsome and polished, but significantly more conservative compared to the QX65’s head-turning silhouette.

For buyers in the Denver area who want their luxury SUV to stand out in a parking lot or on I-25, the QX65 makes a compelling case.

Performance

Under the hood, both vehicles offer turbocharged four-cylinder engines, but the details differ. The 2027 INFINITI QX65 is powered by INFINITI’s 2.0-liter VC-Turbo engine producing 268 horsepower and 286 lb-ft of torque, paired with a 9-speed automatic transmission. All-wheel drive is standard across every QX65 trim level, which is a meaningful advantage for Colorado drivers navigating snow-covered roads and mountain passes.

The 2026 Lexus RX 350 is powered by a 2.4-liter turbocharged inline-four producing 275 horsepower and 317 lb-ft of torque, paired with an 8-speed automatic transmission. However, AWD is not standard on the RX 350 — it’s an added-cost option on most trims, starting at an additional $1,600. For Colorado buyers who rely on all-weather capability, this is a notable consideration.

Advantage: QX65 — standard AWD across all trims means every buyer gets full all-weather confidence without paying extra.

Interior and Comfort

Inside the 2027 INFINITI QX65, buyers are greeted with a premium cabin featuring TailorFit® seating, heated front seats, 12.3” touchscreen display, wireless Apple CarPlay® and Android Auto™, and wireless charging — all standard on the base Luxe trim. The Sport trim adds ventilated front seats and a 16-speaker Klipsch Premium audio system, while the Autograph brings quilted semi-aniline leather upholstery, massaging front seats, heated rear seats, and a 20-speaker Klipsch Reference Premiere.

The 2026 Lexus RX 350 offers a well-appointed interior with NuLuxe synthetic leather upholstery, a 9.8-inch touchscreen with wireless Apple CarPlay® and Android Auto™, and heated front seats.

Advantage: QX65 — more standard premium features at the entry level.

Safety Features

The 2027 INFINITI QX65 comes standard with INFINITI’s impressive safety suite, which includes adaptive cruise control, lane departure prevention, lane centering assist, blind spot intervention,  automatic emergency braking and Pro PILOT Assist (hands-on). Upper trims add the 3D Around View® Monitor with Fixed Views, Invisible Hood View & Front Wide View.

The 2026 Lexus RX 350 is equipped with the Lexus Safety System+ package as standard, covering pre-collision warning with automatic braking, dynamic radar cruise control, lane departure alert with steering assist, and road sign assist.

Both vehicles offer strong safety coverage — this is effectively a tie between two well-equipped luxury SUVs.

Which Is Right for You?

Both are excellent vehicles, and the right choice comes down to your priorities. The Lexus RX 350 is a proven, refined luxury SUV with a slightly lower base price and a reputation for long-term reliability. If a traditional luxury SUV aesthetic and a well-known badge are what you’re after, it is a solid choice.

But if you want a luxury crossover that turns heads, comes with AWD standard, offers more cargo room, and delivers more premium features at every price point — the 2027 INFINITI QX65 is the smarter buy for Denver-area drivers.

Learn More About the 2027 INFINITI QX65 at Mike Ward INFINITI Near Denver

The all-new 2027 INFINITI QX65 is arriving at Mike Ward INFINITI in Highlands Ranch, Colorado this summer. Our team is ready to help you explore the QX65 lineup, discuss trim levels, and find the right vehicle for your lifestyle. Contact us today or browse our new inventory to learn more.

Mike Ward INFINITI | 1800 Lucent Ct, Highlands Ranch, CO 80129 | 303-350-4300

FAQ

Does the 2027 INFINITI QX65 come with all-wheel drive standard?

Yes — unlike many competitors, including the Lexus RX 350, the 2027 INFINITI QX65 includes standard all-wheel drive on every trim level: Luxe, Sport, and Autograph. For Colorado drivers who need all-weather confidence on snowy roads and mountain passes, this is a meaningful advantage with no added cost.

How does the 2027 INFINITI QX65 compare to the Lexus RX 350 in price?

The 2027 INFINITI QX65 starts at $53,990 (Luxe AWD), while the 2026 Lexus RX 350 starts at $52,375 — but that base Lexus price is for front-wheel drive. Adding AWD to the RX 350 brings it to a comparable price point.

What technology features come standard on the 2027 INFINITI QX65?

Every 2027 QX65 comes equipped with a 12.3-inch touchscreen, wireless Apple CarPlay and Android Auto, wireless charging, heated front seats, and TailorFit seating — all standard on the entry-level Luxe trim. Upper trims add ventilated seats, a Klipsch premium audio system, massaging seats, and a 3D Around View Monitor.

Where can I test drive the 2027 INFINITI QX65 near Denver?

The 2027 INFINITI QX65 is arriving this summer at Mike Ward INFINITI, located at 1800 Lucent Ct in Highlands Ranch, Colorado — just a short drive from Denver, Littleton, and Castle Rock. Contact our team at 303-350-4300 or browse our new inventory online to learn more and schedule your test drive.

Verification Disclaimer
“All information in this overview was sourced directly from the official manufacturer’s website and is accurate to the best of our knowledge.